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Research Articles

Deep Learning Models for Autism Diagnosis: A Comprehensive Comparison of Architectures, Performance, and Clinical Applicability

This article provides a systematic analysis of deep learning (DL) approaches for autism spectrum disorder (ASD) diagnosis, addressing the critical need for objective and early screening tools.

Benjamin Bennett
Dec 03, 2025

Brain Size Dichotomy in Autism: A Comparative Analysis of Overgrowth and Undergrowth in Preclinical ASD Models

This review provides a comprehensive analysis of the divergent brain growth phenotypes—overgrowth and undergrowth—observed in Autism Spectrum Disorder (ASD).

Thomas Carter
Dec 03, 2025

Validating Autism Spectrum Disorder Mechanisms: A Cross-Omics Integration Framework for Research and Drug Development

This article synthesizes current methodologies and findings in cross-omics validation for Autism Spectrum Disorder (ASD), addressing the critical need for reproducible and biologically relevant insights for researchers and drug development...

Lucas Price
Dec 03, 2025

Validating Autism Spectrum Disorder Genes through Protein Interaction Networks: Systems Biology Approaches and Clinical Translation

This comprehensive review explores the critical role of protein-protein interaction (PPI) network analysis in validating Autism Spectrum Disorder (ASD) risk genes.

Sophia Barnes
Dec 03, 2025

Decoding Autism Heterogeneity: A Multimodal Neuroimaging Comparison of ALFF, fALFF, and GMV Across ASD Subtypes

This article provides a comprehensive analysis of Amplitude of Low-Frequency Fluctuation (ALFF), fractional ALFF (fALFF), and Gray Matter Volume (GMV) as critical biomarkers for differentiating autism spectrum disorder (ASD) subtypes.

Aubrey Brooks
Dec 03, 2025

Beyond the Spectrum: Decoding Autism Heterogeneity Through Structural and Functional MRI Subtypes

Autism Spectrum Disorder (ASD) is characterized by significant clinical and biological heterogeneity, which has been a major obstacle in understanding its neurobiology and developing effective, targeted treatments.

Logan Murphy
Dec 03, 2025

Decoding Autism Heterogeneity: A Comparative Pathway Analysis of Biologically Distinct Subtypes

Autism spectrum disorder (ASD) is characterized by profound clinical and biological heterogeneity, which has long hindered the development of targeted therapies.

Olivia Bennett
Dec 03, 2025

Decoding Neural Divergence: A Comparative Analysis of Brain Network Differences in Autism and Asperger Syndrome

This review synthesizes contemporary neuroimaging and genetic research to elucidate the distinct and overlapping brain network characteristics of Autism Spectrum Disorder (ASD) and Asperger Syndrome (AS).

Aubrey Brooks
Dec 03, 2025

Validating Autism Candidate Genes: A Comprehensive Guide to the SFARI Gene Database for Researchers

This article provides a complete framework for validating autism spectrum disorder (ASD) candidate genes using the SFARI Gene database.

Ethan Sanders
Dec 03, 2025

Functional Connectivity Subtypes in Autism Spectrum Disorder: A Comprehensive Review for Researchers and Therapeutics Development

This article synthesizes current research on functional connectivity (FC) subtypes in Autism Spectrum Disorder (ASD), addressing the critical need to deconstruct the disorder's pronounced heterogeneity.

David Flores
Dec 03, 2025

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