Research Articles
Global Optimization for Model Tuning: Enhancing Accuracy and Efficiency in Drug Discovery
This article provides a comprehensive guide to global optimization methods for model tuning, tailored for researchers and professionals in drug development.
Optimization Algorithms for Computational Systems Biology: From Model Tuning to Clinical Translation
This article provides a comprehensive review of optimization algorithms powering modern computational systems biology.
Overcoming Parameter Estimation Challenges in Biochemical Pathways: From Data Scarcity to Predictive Models
Parameter estimation is a fundamental yet formidable challenge in building quantitative models of biochemical pathways, essential for metabolic engineering and drug discovery.
High-Throughput Data Analysis in Systems Biology: Streamlining Workflows from Raw Data to Biological Insight
This article provides a comprehensive guide to high-throughput data analysis workflows in systems biology, tailored for researchers and drug development professionals.
From Networks to Cures: How Machine Learning is Revolutionizing Systems Biology and Drug Development
This article explores the transformative impact of machine learning (ML) on systems biology, offering a comprehensive guide for researchers and drug development professionals.
Flux Balance Analysis in Metabolic Engineering: A Comprehensive Guide for Researchers and Drug Developers
This article provides a comprehensive exploration of Flux Balance Analysis (FBA) and its cutting-edge applications in metabolic engineering and drug development.
Stochastic Modeling in Biochemical Systems: From Noise to Knowledge in Drug Development
This article provides a comprehensive overview of stochastic modeling techniques for biochemical systems, essential for researchers and drug development professionals.
Integrating Multi-Omics Data in Systems Biology: From Foundational Concepts to Clinical Applications
This article provides a comprehensive overview of the strategies and computational methods for integrating multi-omics data within a systems biology framework.
Dynamic Modeling of Metabolic Networks: Protocols for Biomedical Research and Therapeutic Discovery
This article provides a comprehensive guide to dynamic modeling of metabolic networks, bridging foundational concepts with advanced applications.
Advanced Optimization Methods for Parameter Estimation in Systems Biology: From Foundations to AI-Driven Approaches
Parameter estimation is a central challenge in building predictive computational models of biological systems.