Research Articles
Integrative Multi-Omics Approaches in Autism Spectrum Disorder: From Molecular Mechanisms to Precision Medicine
This comprehensive review explores how multi-omics technologies are revolutionizing our understanding of Autism Spectrum Disorder (ASD) by integrating genomic, transcriptomic, proteomic, metabolomic, and microbiome data.
Convergent Mechanisms in Autism Spectrum Disorder: From Genetic Heterogeneity to Unified Pathophysiological Pathways
Autism Spectrum Disorder (ASD) presents extraordinary genetic heterogeneity, with hundreds of risk genes identified.
Decoding Autism: Biochemical Pathways, Genetic Subtypes, and Precision Medicine Approaches
This article synthesizes the latest breakthroughs in understanding the biochemical and genetic architecture of Autism Spectrum Disorder (ASD).
Autism as a Complex Systems Disorder: Decoding Biological Heterogeneity for Precision Therapeutics
This article synthesizes the latest research reconceptualizing Autism Spectrum Disorder (ASD) as a complex systems disorder, moving beyond a monolithic condition to a convergence of distinct biological subtypes.
Network Topology of ASD Risk Genes: From Genetic Architecture to Therapeutic Discovery
This article synthesizes current research on the network topology of Autism Spectrum Disorder (ASD) risk genes, addressing a core challenge in the field: bridging the gap between hundreds of identified...
SFARI Gene Database: A Comprehensive Systems Analysis for Autism Research and Drug Discovery
This systems analysis examines SFARI Gene as an integrated resource accelerating autism spectrum disorder (ASD) research.
From Genes to Systems: Decoding Autism Heterogeneity Through a Systems Biology Lens
This article explores the paradigm shift in autism research from single-gene causation models to systems biology frameworks that address extreme genetic heterogeneity.
Mapping the Autism Interactome: How Protein-Protein Interaction Networks Are Revolutionizing ASD Research and Drug Discovery
This article synthesizes the latest advances in mapping protein-protein interaction (PPI) networks to decode the complex biology of Autism Spectrum Disorder (ASD).
Systems Biology and Autism Spectrum Disorder: Decoding Heterogeneity for Precision Therapeutics
This article provides a comprehensive analysis of the systems biology approach to Autism Spectrum Disorder (ASD), a paradigm shift moving beyond viewing ASD as a single condition.
Network Analysis in Drug Repurposing: From Predictive Models to Clinical Validation
This comprehensive review explores the transformative role of network analysis in predicting and validating drug repurposing candidates.